Click chemistry under non-classical reaction conditions.

@article{Kappe2010ClickCU,
  title={Click chemistry under non-classical reaction conditions.},
  author={C. Oliver Kappe and Erik Van der Eycken},
  journal={Chemical Society reviews},
  year={2010},
  volume={39 4},
  pages={1280-90}
}
First described almost a decade ago, "click" reactions such as the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) are widely used today in organic and medicinal chemistry, in the polymer and material science field, and in chemical biology. While most click reactions can be performed at room temperature there are instances where some form of process… CONTINUE READING