Click chemistry: a route to designing and preparing pseudo-biospecific immunoadsorbent for IgG adsorption.


L-histidine is a promising alternative to expensive protein ligands for the adsorption of IgG due to its high selectivity, no toxicity and low cost; while click chemistry can improve the reaction selectivity between the ligands and the support matrix under mild reaction conditions. Thus, using L-histidine as a ligand and original sepharose gel as a support… (More)
DOI: 10.1016/j.jchromb.2012.05.007


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