Clenbuterol treatment affects myosin heavy chain isoforms and MyoD content similarly in intact and regenerated soleus muscles.

@article{Bricout2004ClenbuterolTA,
  title={Clenbuterol treatment affects myosin heavy chain isoforms and MyoD content similarly in intact and regenerated soleus muscles.},
  author={V{\'e}ronique-Aur{\'e}lie Bricout and Bernard Serrurier and A X Bigard},
  journal={Acta physiologica Scandinavica},
  year={2004},
  volume={180 3},
  pages={271-80}
}
AIMS Pharmacological treatment with the beta2-adrenoceptor agonist clenbuterol is known to induce a slow-to-fast fibre type and myosin heavy chain (MHC) isoform transition in intact muscle. This study examined the sensitivity of regenerated soleus muscle to 4 weeks of clenbuterol treatment (2 mg kg-1 day-1). METHODS Female Wistar rats were divided into two groups: vehicle treated (n = 8) and clenbuterol treated (n = 8). The clenbuterol effects on MHC and MyoD expression were examined in… CONTINUE READING

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