Cleft lip with or without cleft palate: implication of the heavy chain of non-muscle myosin IIA.

@article{Martinelli2007CleftLW,
  title={Cleft lip with or without cleft palate: implication of the heavy chain of non-muscle myosin IIA.},
  author={Marcella Martinelli and Mariateresa Di Stazio and Luca Scapoli and Jlenia Marchesini and Filomena di Bari and Furio Pezzetti and Francesco Carinci and Annalisa Palmieri and Paolo Carinci and Anna Savoia},
  journal={Journal of medical genetics},
  year={2007},
  volume={44 6},
  pages={
          387-92
        }
}
Non-syndromic cleft lip with or without palate (CL/P) is one of the most common malformations among live births, but most of the genetic components and environmental factors involved remain to be identified. Among the different causes, MYH9, the gene encoding for the heavy chain of non-muscle myosin IIA, was considered a potential candidate, because it was found to be abundantly and specifically expressed in epithelial cells of palatal shelves before fusion. After fusion, its expression level… CONTINUE READING
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