Cleavage site selection by M1 RNA the catalytic subunit of Escherichia coli RNase P, is influenced by pH.

@article{Kufel1994CleavageSS,
  title={Cleavage site selection by M1 RNA the catalytic subunit of Escherichia coli RNase P, is influenced by pH.},
  author={Joanna Kufel and Leif A. Kirsebom},
  journal={Journal of molecular biology},
  year={1994},
  volume={244 5},
  pages={511-21}
}
We have studied cleavage site selection by M1 RNA, the catalytic subunit of Escherichia coli RNase P, under various reaction conditions using tRNA precursors which are cleaved at two positions. Our results showed that the preference of cleavage site changed with variations in pH or Mg2+ concentration. By contrast, no difference in cleavage site selection… CONTINUE READING