Cleavage of dehydroalanine-containing peptides with mercuric acetate.
@article{Edge1981CleavageOD, title={Cleavage of dehydroalanine-containing peptides with mercuric acetate.}, author={Albert S. B. Edge and Patrick Weber}, journal={International journal of peptide and protein research}, year={1981}, volume={18 1}, pages={ 1-5 } }
The dehydroalanine containing peptides glycyldehydroalanine and t-butyloxy-carbonyl-L-alanyldehydroalanyl-beta-methyl-D, L-aspartic acid methyl ester were synthesized, respectively, from chloroacetamide and pyruvate and from t-butyloxycarbonyl-L-alanyl-S-methyl-L-cysteinyl-beta-methyl-D, L-aspartic acid methyl ester. They were reacted with mercuric acetate in water, 50% methanol and dimethylformamide at 25 degrees and at 80 degrees for various time periods. Reaction proceeded to yield an amino…
One Citation
Synthesis of Peptides with α,β‐Dehydroamino Acids, I. Synthesis of N‐Benzyloxycarbonyl and N‐Trifluoroacetyl Dipeptides of Dehydroalanine and Dehydrophenylalanine
- Chemistry
- 1984
Condensation of amides of N-(benzyloxycarbonyl)- and N-(trifluoroacetyl)amino acid with pyruvic and phenylpyruvic acid yields, in the presence of p-toluenesulfonic acid as a catalyst,…
References
SHOWING 1-10 OF 19 REFERENCES
Cyclic peptides. V. Synthesis of AM-toxin II and its analog.
- ChemistryInternational journal of peptide and protein research
- 1978
A cyclic tetradepsipeptide with a sequence corresponding to AM-toxin II (a phytotoxic peptide) was synthesized in order to confirm the proposed structure by a conventional method and showed extremely weak activity.
Selective cleavage and modification of peptides and proteins.
- Biology, ChemistryAdvances in protein chemistry
- 1970
Enzymatic synthesis of deoxyribonucleic acid. XXVII. Chemical modifications of deoxyribonucleic acid polymerase.
- Biology, ChemistryThe Journal of biological chemistry
- 1969
Aminosäure‐Synthesen mit α‐Acylamino‐Acrylestern
- Chemistry
- 1957
Durch eine verbesserte Bergmann-Grafe-Kondensation, bei der das Reaktionswasser durch azeotrope Destillation entfernt wird, konnten aus Brenztraubensaure und mehreren Saureamiden einige neue…