Cleavage of bleomycin hydrolase by caspase-3 during apoptosis.


Bleomycin hydrolase (BLH) affects bleomycin chemotherapy through inactivation of bleomycin with deamination. As a neutral cysteine protease, it also plays various roles in physiological conditions and diseases. However, its mechanism of degradation remains unclear. In the present study, we showed that the levels of BLH were significantly reduced during… (More)
DOI: 10.3892/or.2013.2484


Cite this paper

@article{Chen2013CleavageOB, title={Cleavage of bleomycin hydrolase by caspase-3 during apoptosis.}, author={Yang Chen and Rong Zhen Xu and Jianguo Chen and Xiaoyu Li and Qiyang He}, journal={Oncology reports}, year={2013}, volume={30 2}, pages={939-44} }