Cleavage of Histone 3 by Cathepsin D in the Involuting Mammary Gland

@inproceedings{KhalkhaliEllis2014CleavageOH,
  title={Cleavage of Histone 3 by Cathepsin D in the Involuting Mammary Gland},
  author={Zhila Khalkhali-Ellis and William Goossens and Naira V. Margaryan and Mary J. C. Hendrix},
  booktitle={PloS one},
  year={2014}
}
The post-lactational regression of mammary gland is a complex multi-step process designed to conserve the biological function of the gland for next pregnancy. This developmental stage is a biological intrigue with great relevance to breast cancer research, and thus has been the subject of intensive scrutiny. Multipronged studies (microarray, proteomics profiling, animal knock-out models) have provided a repertoire of genes critical to involution. However, the caveat of these approaches remains… CONTINUE READING
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