Clearance of albumin following ultrasound-induced blood-brain barrier opening is mediated by glial but not neuronal cells.

@article{Alonso2011ClearanceOA,
  title={Clearance of albumin following ultrasound-induced blood-brain barrier opening is mediated by glial but not neuronal cells.},
  author={Angelika Alonso and Eileen Reinz and Marc Fatar and Michael Hennerici and Stephen Meairs},
  journal={Brain research},
  year={2011},
  volume={1411},
  pages={9-16}
}
Ultrasound-mediated opening of the blood-brain barrier (BBB) in the presence of gas-filled microbubbles is a potential strategy for drug delivery across the blood-brain barrier to promote regeneration after ischemic stroke. However, related bioeffects and potential side-effects that could limit a translation into clinical application are poorly understood so far. We therefore examined the clearance of extravasated albumin following ultrasound-mediated BBB opening. Autofluorescence of albumin… CONTINUE READING

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Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI - guided focused ultrasound

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