Clearance and excretion of intratracheally and orally administered aflatoxin B1 in the rat.


The pharmacokinetic disposition of intratracheally (i/t) and orally administered [3H]AFB1 was studied in male Sprague-Dawley rats. Blood, urine and faeces were collected at selected intervals following administration of a single i/t or oral dose of AFB1 (600 micrograms/kg) in saline. Blood-concentration data from both groups approximated a two-compartment… (More)


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