Clear cell sarcoma of soft tissue: a clinicopathologic, immunohistochemical, and molecular analysis of 33 cases.

@article{Hisaoka2008ClearCS,
  title={Clear cell sarcoma of soft tissue: a clinicopathologic, immunohistochemical, and molecular analysis of 33 cases.},
  author={Masanori Hisaoka and Tsuyoshi Ishida and Tseng-tong Kuo and Atsuji Matsuyama and Tetsuo Imamura and Kazunori Nishida and Hiroshi Kuroda and Yoshiaki Inayama and Hisashi Oshiro and Hiroshi Kobayashi and Takashi Nakajima and Toshio Fukuda and Keisuke Ae and Hiroshi Hashimoto},
  journal={The American journal of surgical pathology},
  year={2008},
  volume={32 3},
  pages={452-60}
}
Clear cell sarcoma (CCS) of soft tissue is a rare sarcoma with morphologic similarities to malignant melanoma but a distinct genetic background including a chromosomal translocation, t(12;22)(q13;q12), or a resultant EWSR1-ATF1 fusion gene. In addition, the tumors occurring in the gastrointestinal tract may have a variant fusion gene EWSR1-CREB1. This study analyzed the clinicopathologic and molecular genetic features of 33 CCSs of soft tissue. The patients' ages ranged from 13 to 73 years… CONTINUE READING
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