Clear cell papulosis of the skin. A new entity with histogenetic implications for cutaneous Paget's disease.

@article{Kuo1987ClearCP,
  title={Clear cell papulosis of the skin. A new entity with histogenetic implications for cutaneous Paget's disease.},
  author={Tseng-tong Kuo and Henry Hin-Lee Chan and Shun Jen Hsueh},
  journal={The American journal of surgical pathology},
  year={1987},
  volume={11 11},
  pages={
          827-34
        }
}
A new skin condition characterized by multiple white papular eruptions was observed in two young brothers. Histologic study revealed many benign pagetoid clear cells in the basal layer of the acanthotic epidermis with decreased pigmentation. These cells contained cytoplasmic mucin and were positive for keratin AE1/AE3, carcinoembryonic antigen, and epithelial membrane antigen. The staining pattern was identical to that of extramammary Paget's disease. The presence of mucin granules and… CONTINUE READING
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