Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064

@inproceedings{Vasconcelos2013ClavulanicAP,
  title={Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064},
  author={Eliton da Silva Vasconcelos and Vanderlei Aparecido de Lima and Leandro Seiji Goto and Isara Lourdes Cruz-Hern{\'a}ndez and Carlos Osamu Hokka},
  booktitle={Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]},
  year={2013}
}
Clavulanic acid (CA) is a powerful inhibitor of the beta-lactamases, enzymes produced by bacteria resistants to penicillin and cefalosporin. This molecule is produced industrially by strains of Streptomyces clavuligerus in complex media which carbon and nitrogen resources are supplied by inexpensive compounds still providing high productivity. The genetic… CONTINUE READING