Claustrum sign in a child with refractory status epilepticus after febrile illness: why does it happen?

  title={Claustrum sign in a child with refractory status epilepticus after febrile illness: why does it happen?},
  author={Guilherme Silva and Sylvia Jacob and Cl{\'a}udia Melo and D{\'i}lio Alves and Dias Costa},
  journal={Acta Neurologica Belgica},
A 6-year-old female patient with normal psychomotor development was admitted at our hospital with status epilepticus. The patient had been suffering from headache, anorexia and fever in the preceding week. On the day of admission, the patient developed focal tonic–clonic movements in the left superior limb that responded to intravenous diazepam. However, the patient did not recover to normal mental status. Therapy included other anti-epileptic drugs (valproate, phenytoin and levetiracetam… 
Bilateral fronto-insular FLAIR hyperintensities: discussion on a case of new-onset refractory status epilepticus
It is suggested that bilateral fronto-insular vasogenic oedema in a patient with refractory SE and fever could be compatible with NORSE, a clinical entity characterised by new-onset refraction SE without any evidence of active structural/metabolic or toxic cause at the time of diagnosis.
A pilot study of the role of the claustrum in attention and seizures in rats
Findings from the operant conditioning task suggest stimulation of the claustrum can alter attention or awareness, and KA seizures showed early involvement of the enclustrum, a finding that supports a possible role of theaclustrum in the alteration of consciousness that accompanies dyscognitive seizures.
A comprehensive protocol for manual segmentation of the human claustrum and its sub-regions using high-resolution MRI
A comprehensive manual segmentation protocol to delineate Cl based on a cellular level brain atlas is developed and it is required to assess the reliability of the protocol so that it can be used for future anatomical studies of neuropsychiatric disorders, including epilepsy and schizophrenia.
Internal Subdivisions of the Marmoset Claustrum Complex: Identification by Myeloarchitectural Features and High Field Strength Imaging
The results indicate that the classically defined marmoset claustrum includes at least two major subdivisions, which correspond to the dorsal endopiriform and insular claUSTrum nuclei, as described in other species, and that the dorsal EndopIRiform nucleus (DEnD) contains architecturally distinct compartments.
Automated Human Claustrum Segmentation using Deep Learning Technologies
This paper proposes a fully automated approach that aims to segment the human claustrum for analytical purposes and applied a U-Net CNN model to segment it from a MRI dataset.
AM-UNet: automated mini 3D end-to-end U-net based network for brain claustrum segmentation
Recent advances in deep learning (DL) have provided promising solutions to medical image segmentation. Among existing segmentation approaches, the U-Net-based methods have been used widely. However,


Claustrum damage and refractory status epilepticus following febrile illness
This is a hypothesis-generating study of a preliminary nature supporting the role of the claustrum in postfebrile de novo SE; future prospective studies are needed to delineate the specificity of this condition, its pathogenesis, and the etiology.
New-Onset Refractory Status Epilepticus with Claustrum Damage: Definition of the Clinical and Neuroimaging Features
Febrile illness-related SE associated with bilateral claustrum hyperintensity on MRI represents a condition with defined clinical features and a presumed but unidentified autoimmune etiology.
Severe transitory encephalopathy with reversible lesions of the claustrum
Reversible bilateral lesions of the claustrum and external capsule in a 12-year-old girl suffering from a severe, transitory encephalopathy are reported; repeated cerebrospinal fluid and blood tests were negative for herpes simplex virus and other infectious agents.
Transient MR signal changes in patients with generalized tonicoclonic seizure or status epilepticus: periictal diffusion-weighted imaging.
The MR signal changes that occur after generalized tonicoclonic seizure or status epilepticus are transient increase of signal intensity and swelling at the cortical gray matter, subcortical white matter, or hippocampus on periictal T2- Weighted and diffusion-weighted images.
What is the function of the claustrum?
  • F. Crick, C. Koch
  • Biology, Medicine
    Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2005
What is known about the claustrum is summarized, its possible relationship to the processes that give rise to integrated conscious percepts is speculated, mechanisms that enable information to travel widely within the claUSTrum are proposed and experiments to address these questions are discussed.
periictal diffusion-weighted imaging
  • Am J Neuroradiol 22:1149–1160 Acta Neurol Belg
  • 2018