Claudin proteins in human cancer: promising new targets for diagnosis and therapy.

@article{Morin2005ClaudinPI,
  title={Claudin proteins in human cancer: promising new targets for diagnosis and therapy.},
  author={Patrice J. Morin},
  journal={Cancer research},
  year={2005},
  volume={65 21},
  pages={9603-6}
}
The tight junction proteins claudins are abnormally regulated in several human cancers. In particular, claudin-3 and claudin-4 are frequently overexpressed in several neoplasias, including ovarian, breast, pancreatic, and prostate cancers. Although the exact roles of these proteins in tumorigenesis are still being uncovered, it is clear that they represent promising targets for cancer detection, diagnosis, and therapy. 
Highly Influential
This paper has highly influenced 16 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.
240 Citations
50 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 240 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Similar Papers

Loading similar papers…