Claudin-1, -3 and -4 proteins and mRNA expression in benign and malignant breast lesions: a research study

Abstract

We compared levels of protein and mRNA expression of three members of the claudin (CLDN) family in malignant breast tumours and benign lesions. Altogether, 56 sections from 52 surgically resected breast specimens were analyzed for CLDN1, CLDN3 and CLDN4 expression by immunohistochemistry. mRNA was also analyzed using real-time PCR in 17 of the 52 cases… (More)
DOI: 10.1186/bcr983

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