Clathrin assembly protein AP-2 induces aggregation of membrane vesicles: a possible role for AP-2 in endosome formation

@article{Beck1992ClathrinAP,
  title={Clathrin assembly protein AP-2 induces aggregation of membrane vesicles: a possible role for AP-2 in endosome formation},
  author={Kenneth A Beck and Michael Chang and Frances M. Brodsky and James H. Keen},
  journal={The Journal of Cell Biology},
  year={1992},
  volume={119},
  pages={787 - 796}
}
We have examined the in vitro behavior of clathrin-coated vesicles that have been stripped of their surface coats such that the majority of the clathrin is removed but substantial amounts of clathrin assembly proteins (AP) remain membrane-associated. Aggregation of these stripped coated vesicles (s-CV) is observed when they are placed under conditions that approximate the pH and ionic strength of the cell interior (pH 7.2, approximately 100 mM salt). This s-CV aggregation reaction is rapid (t1… CONTINUE READING
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A novel IP, modulated potassium channel from cerebellum is related to clathrin assembly proteins

  • A. P. Timerman, M. Mayrleitner, +4 authors S. Fleischer.
  • FASEB (Fed. Am. Soc. Exp. Biol.) J. 6:513a.
  • 1992
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