Clathrate nanostructures for mass spectrometry

@article{Northen2007ClathrateNF,
  title={Clathrate nanostructures for mass spectrometry},
  author={Trent R. Northen and {\'O}. Yanes and Michael T. Northen and D. Marrinucci and Winnie Uritboonthai and J. Apon and S. Golledge and A. Nordstroem and G. Siuzdak},
  journal={Nature},
  year={2007},
  volume={449},
  pages={1033-1036}
}
  • Trent R. Northen, Ó. Yanes, +6 authors G. Siuzdak
  • Published 2007
  • Chemistry, Medicine
  • Nature
  • The ability of mass spectrometry to generate intact biomolecular ions efficiently in the gas phase has led to its widespread application in metabolomics, proteomics, biological imaging, biomarker discovery and clinical assays (namely neonatal screens). Matrix-assisted laser desorption/ionization (MALDI) and electrospray ionization have been at the forefront of these developments. However, matrix application complicates the use of MALDI for cellular, tissue, biofluid and microarray analysis and… CONTINUE READING
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