Classifying asthma severity in children: mismatch between symptoms, medication use, and lung function.

@article{Bacharier2004ClassifyingAS,
  title={Classifying asthma severity in children: mismatch between symptoms, medication use, and lung function.},
  author={L. Bacharier and R. Strunk and D. Mauger and D. White and R. Lemanske and C. Sorkness},
  journal={American journal of respiratory and critical care medicine},
  year={2004},
  volume={170 4},
  pages={
          426-32
        }
}
Current guidelines for asthma care categorize asthma severity based on the frequency of asthma symptoms, medication use, and lung function measures. The objective of this study was to determine whether lung function measures are consistent with levels of asthma severity as defined by the National Asthma Education and Prevention Program/Expert Panel Report 2 Guidelines. Parents of children aged 5-18 years with asthma seen in two outpatient subspecialty clinics completed questionnaires regarding… Expand
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References

SHOWING 1-10 OF 27 REFERENCES
Categorizing asthma severity.
TLDR
Applying the Expert Panel II recommended method for asthma severity categorization to a large data set illustrates that a single variable, nocturnal symptoms, determined to aLarge extent overall categorization. Expand
Relationships between duration of asthma and asthma severity among children in the Childhood Asthma Management Program (CAMP)
TLDR
It is demonstrated that asthma duration is associated with lower lung function, greater methacholine responsiveness, more asthma symptomatology, and greater use of as-needed albuterol, which are all measures of asthma severity. Expand
Relationship between increased airway responsiveness and asthma severity in the childhood asthma management program.
TLDR
Evidence is provided that the degree of airway responsiveness is linked to disease severity in children with mild to moderate asthma. Expand
Nocturnal awakening caused by asthma in children with mild-to-moderate asthma in the childhood asthma management program.
TLDR
Nocturnal awakening occurred in one third of the children with mild-to-moderate asthma during a month of relative stability and appears to be an indicator of asthma that is becoming increasingly severe. Expand
Effects of asthma on pulmonary function in children. A longitudinal population-based study.
TLDR
It is predicted that a female who develops asthma at age 7 would experience a 5% reduction in FEV1 by age 10 and a 7% deficit by age 15, and from this analysis, it would predict that a male who develops asthmatic disease at age 9 would experience an 8% deficit. Expand
Relationship between airway obstruction and respiratory symptoms in adult asthmatics.
TLDR
The results support the recommendation to measure airway obstruction objectively when assessing adult patients with chronic asthma and suggest subjective improvement in asthma symptoms may occur without improvement in the level ofAirway obstruction following treatment. Expand
Lack of correlation between clinical patterns of asthma and airway obstruction.
TLDR
The high percentage of discordance between clinical classification and obstruction index in the subjects with IEA can be caused by the persistence of abnormalities of the respiratory function without clinical symptoms, and the presence of a normal obstruction index can be explained by the pharmacologic therapies. Expand
FEV(1) is associated with risk of asthma attacks in a pediatric population.
TLDR
The strong association between FEV(1)% and risk of asthma attack over the subsequent year supports an emphasis on objective measures of lung function in assessment of risk for adverse asthma outcomes. Expand
Childhood asthma and adult lung function.
TLDR
An age-matched group of 247 subjects who had had asthma as children and 39 control subjects were studied with lung function and bronchial reactivity testing at the age of 28 years, finding no association was found between reactivity and loss of ventilatory capacity since 21 years of age. Expand
National trends in asthma visits and asthma pharmacotherapy, 1978-2002.
TLDR
Asthma pharmacotherapy has changed extensively in the past 25 years, and practices over the last decade are increasingly consistent with evidence-based guidelines, which might have contributed to the lack of a recent increase in asthma visits. Expand
...
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2
3
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