Classifying Autism Spectrum Disorders by ADI-R: Subtypes or Severity Gradient?

  title={Classifying Autism Spectrum Disorders by ADI-R: Subtypes or Severity Gradient?},
  author={Hannah Cholemkery and Juliane E Medda and Thomas Lempp and Christine M. Freitag},
  journal={Journal of autism and developmental disorders},
  volume={46 7},
To reduce phenotypic heterogeneity of Autism spectrum disorders (ASD) and add to the current diagnostic discussion this study aimed at identifying clinically meaningful ASD subgroups. Cluster analyses were used to describe empirically derived groups based on the Autism Diagnostic Interview-revised (ADI-R) in a large sample of n = 463 individuals with ASD aged 3-21. Three clusters were observed. Most severely affected individuals regarding all core symptoms were allocated to cluster 2. Cluster 3… CONTINUE READING
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