Classification of schizophrenia patients and healthy controls from structural MRI scans in two large independent samples

@article{Nieuwenhuis2012ClassificationOS,
  title={Classification of schizophrenia patients and healthy controls from structural MRI scans in two large independent samples},
  author={Mireille Nieuwenhuis and Neeltje E. M. van Haren and Hilleke E. Hulshoff Pol and Wiepke Cahn and Ren{\'e} S. Kahn and Hugo G. Schnack},
  journal={NeuroImage},
  year={2012},
  volume={61 3},
  pages={606-12}
}
The purpose of this study is to create a model that can classify schizophrenia patients and healthy controls based on whole brain gray matter densities (voxel-based morphometry, VBM) from structural magnetic resonance imaging (MRI) scans. In addition, we investigated the stability of the accuracy of the models, when built with different sample sizes. Using a support vector machine, we built a model from 239 subjects (128 patients and 111 healthy controls) and classified 71.4% correct (leave-one… CONTINUE READING
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