Classification of pathologic response to neoadjuvant therapy in esophageal and junctional cancer: assessment of existing measures and proposal of a novel 3-point standard.

@article{Donohoe2013ClassificationOP,
  title={Classification of pathologic response to neoadjuvant therapy in esophageal and junctional cancer: assessment of existing measures and proposal of a novel 3-point standard.},
  author={Claire L. Donohoe and Naoimh J O'Farrell and T. P. Grant and Sin{\'e}ad King and Lindsey Anne Clarke and Cian B. Muldoon and John Vincent Reynolds},
  journal={Annals of surgery},
  year={2013},
  volume={258 5},
  pages={784-92; discussion 792}
}
OBJECTIVE To assess existing measures of pathologic response to neoadjuvant therapy in esophageal and junctional cancer, and to recommend an optimum classification. BACKGROUND Multimodal therapy is increasingly the standard of care for locally advanced esophageal cancer. Numerous measures of pathologic response have been studied; however, no international standardization exists and no measure is incorporated into the current American Joint Committee on Cancer staging system. METHODS A total… CONTINUE READING