Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra.

@article{Jaumot2009ClassificationON,
  title={Classification of nucleic acids structures by means of the chemometric analysis of circular dichroism spectra.},
  author={Joaquim Jaumot and Ram{\'o}n Eritja and Susana Navea and Raimundo Gargallo},
  journal={Analytica chimica acta},
  year={2009},
  volume={642 1-2},
  pages={117-26}
}
DNA can adopt structures in solution apart from the well-known Watson-Crick double helix, ranging from disordered single strands to high-order structures such as triplexes or quadruplexes. Moreover, different topologies can be adopted depending on the polarity of the DNA strands. The elucidation of the structure and topology adopted by a DNA sequence is usually carried out by means of spectroscopic techniques, such as circular dichroism. In this work, the ability of several chemometric methods… CONTINUE READING

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