Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors

@inproceedings{Yip2011ClassificationOH,
  title={Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors},
  author={Kevin Y. Yip and Chao Cheng and Nitin Bhardwaj and J. Ben Brown and Jing Leng and Anshul Kundaje and Joel S. Rozowsky and Ewan Birney and Peter J. Bickel and Michael P. Snyder and Mark B Gerstein},
  booktitle={Genome Biology},
  year={2011}
}
Transcription factors function by binding different classes of regulatory elements. The Encyclopedia of DNA Elements (ENCODE) project has recently produced binding data for more than 100 transcription factors from about 500 ChIP-seq experiments in multiple cell types. While this large amount of data creates a valuable resource, it is nonetheless overwhelmingly complex and simultaneously incomplete since it covers only a small fraction of all human transcription factors. As part of the… CONTINUE READING
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