Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein, MolA.

@article{TiradoLee2011ClassificationOA,
  title={Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein, MolA.},
  author={Leidamarie Tirado-Lee and Allen Lee and Douglas C Rees and Heather W. Pinkett},
  journal={Structure},
  year={2011},
  volume={19 11},
  pages={1701-10}
}
molA (HI1472) from H. influenzae encodes a periplasmic binding protein (PBP) that delivers substrate to the ABC transporter MolB(2)C(2) (formerly HI1470/71). The structures of MolA with molybdate and tungstate in the binding pocket were solved to 1.6 and 1.7 Å resolution, respectively. The MolA-binding protein binds molybdate and tungstate, but not other oxyanions such as sulfate and phosphate, making it the first class III molybdate-binding protein structurally solved. The ∼100 μM binding… CONTINUE READING

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Cellular uptake of molybdenum and tungsten

  • WR Hagen
  • Coordination Chemistry Reviews
  • 2011
Highly Influential
4 Excerpts

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