Classification and characterization of human endogenous retroviruses; mosaic forms are common

  title={Classification and characterization of human endogenous retroviruses; mosaic forms are common},
  author={Laura Vargiu and Patricia Rodriguez-Tom{\'e} and G{\"o}ran O. Sperber and Marta Cadeddu and Nicole Grandi and Vidar Blikstad and Enzo Tramontano and Jonas Blomberg},
Human endogenous retroviruses (HERVs) represent the inheritance of ancient germ-line cell infections by exogenous retroviruses and the subsequent transmission of the integrated proviruses to the descendants. ERVs have the same internal structure as exogenous retroviruses. While no replication-competent HERVs have been recognized, some retain up to three of four intact ORFs. HERVs have been classified before, with varying scope and depth, notably in the RepBase/RepeatMasker system. However… CONTINUE READING
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