• DOI:10.1124/pr.112.005983
Corpus ID: 7764903

Classification, Functions, and Clinical Relevance of Extracellular Vesicles

@article{Pol2012ClassificationFA,
  title={Classification, Functions, and Clinical Relevance of Extracellular Vesicles},
  author={E. van der Pol and A. B{\"o}ing and P. Harrison and A. Sturk and R. Nieuwland},
  journal={Pharmacological Reviews},
  year={2012},
  volume={64},
  pages={676 - 705}
}

E. van der Pol, A. Böing, +2 authors R. Nieuwland

Published 2012

Biology, Medicine

Pharmacological Reviews

Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into their environment. Why do cells release vesicles? Initial studies showed that eukaryotic vesicles are used to remove obsolete cellular molecules. Although this release of vesicles is beneficial to the cell, the vesicles can also be a danger to their environment, for instance in blood, where vesicles can provide a surface supporting coagulation. Evidence is accumulating that vesicles are cargo containers… CONTINUE READING

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