Classics in Chemical Neuroscience: Memantine.


Memantine was the first breakthrough medication for the treatment of moderate to severe Alzheimer's disease (AD) patients and represents a fundamentally new mechanism of action (moderate-affinity, uncompetitive, voltage-dependent, N-methyl-d-aspartate (NMDA) receptor antagonist that exhibits fast on/off kinetics) to modulate glutamatergic dysfunction. Since… (More)
DOI: 10.1021/acschemneuro.7b00270


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics