Classical cadherins control nucleus and centrosome position and cell polarity

  title={Classical cadherins control nucleus and centrosome position and cell polarity},
  author={Isabelle Dupin and Emeline Camand and Sandrine Etienne-Manneville},
  booktitle={The Journal of cell biology},
Control of cell polarity is crucial during tissue morphogenesis and renewal, and depends on spatial cues provided by the extracellular environment. Using micropatterned substrates to impose reproducible cell-cell interactions, we show that in the absence of other polarizing cues, cell-cell contacts are the main regulator of nucleus and centrosome positioning, and intracellular polarized organization. In a variety of cell types, including astrocytes, epithelial cells, and endothelial cells… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 84 extracted citations

Cell-Based Microarrays

Methods in Molecular Biology • 2018
View 20 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…