Classical Complement Pathway Activation in the Kidneys of Women With Preeclampsia.

@article{Penning2015ClassicalCP,
  title={Classical Complement Pathway Activation in the Kidneys of Women With Preeclampsia.},
  author={Marlies E. Penning and Jamie S. Chua and Cees van Kooten and Malu Zandbergen and Aletta Atje Jacoba Buurma and Joke M. Schutte and Jan Anthonie Bruijn and Eliyahu V. Khankin and Kitty W M Bloemenkamp and Siddharth Karumanchi and Hans J. Baelde},
  journal={Hypertension},
  year={2015},
  volume={66 1},
  pages={117-25}
}
A growing body of evidence suggests that complement dysregulation plays a role in the pathogenesis of preeclampsia. The kidney is one of the major organs affected in preeclampsia. Because the kidney is highly susceptible to complement activation, we hypothesized that preeclampsia is associated with renal complement activation. We performed a nationwide… CONTINUE READING