Class effects of tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia

@article{Giles2009ClassEO,
  title={Class effects of tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia},
  author={F J Giles and M E O'Dwyer and Ronan T Swords},
  journal={Leukemia},
  year={2009},
  volume={23},
  pages={1698-1707}
}
Tyrosine kinase inhibitors have revolutionized the treatment of chronic myeloid leukemia (CML), offering patients several targeted therapeutic options that provide the possibility of sustained remissions and prolonged survival. With the availability of imatinib, nilotinib and dasatinib, physicians must weigh the efficacy and safety profile of each agent when choosing the best therapeutic option for individual patients. Each agent targets tyrosine kinases within the cell uniquely to cause the… 
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