Class IV-S versus class IV-G lupus nephritis: clinical and morphologic differences suggesting different pathogenesis.

@article{Hill2005ClassIV,
  title={Class IV-S versus class IV-G lupus nephritis: clinical and morphologic differences suggesting different pathogenesis.},
  author={Gary S. Hill and Michel Delahousse and Dominique Nochy and Jean Bari{\'e}ty},
  journal={Kidney international},
  year={2005},
  volume={68 5},
  pages={2288-97}
}
BACKGROUND A recently proposed reclassification of lupus nephritis divides class IV (diffuse proliferative) lupus nephritis into those cases with predominantly segmental proliferative lesions (class IV-S) and those with predominantly global proliferative lesions (class IV-G). This report explores the validity of this distinction and possible differences in pathogenesis between the 2 types of lesions. METHODS Patients from a previously reported series of severe lupus nephritis, with initial… CONTINUE READING