Class III beta-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology.

@article{Katsetos2003ClassIB,
  title={Class III beta-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology.},
  author={Christos D. Katsetos and Agust{\'i}n Legido and Elias Perentes and Sverre J. M{\"o}rk},
  journal={Journal of child neurology},
  year={2003},
  volume={18 12},
  pages={851-66; discussion 867}
}
The expression of the cytoskeletal protein class III beta-tubulin isotype is reviewed in the context of human central nervous system development and neoplasia. Compared to systemic organs and tissues, class III beta-tubulin is abundant in the brain, where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar neurogenesis, the distribution of class III beta-tubulin is neuron associated, exhibiting different temporospatial gradients in the neuronal… CONTINUE READING