Class III β-Tubulin and γ-Tubulin are Co-expressed and Form Complexes in Human Glioblastoma Cells

@article{Katsetos2007ClassI,
  title={Class III β-Tubulin and γ-Tubulin are Co-expressed and Form Complexes in Human Glioblastoma Cells},
  author={Christos D. Katsetos and Eduarda Dr{\'a}berov{\'a} and Barbora {\vS}mejkalov{\'a} and G. Sreenivasula Reddy and Louise Bertrand and J. P. de Chadarevian and Agust{\'i}n Legido and Jonathan Nissanov and Peter W. Baas and Pavel Dr{\'a}ber},
  journal={Neurochemical Research},
  year={2007},
  volume={32},
  pages={1387-1398}
}
We have previously shown that the neuronal-associated class III β-tubulin isotype and the centrosome-associated γ-tubulin are aberrantly expressed in astrocytic gliomas (Cell Motil Cytoskeleton 2003, 55:77-96; J Neuropathol Exp Neurol 2006, 65:455–467). Here we determined the expression, distribution and interaction of βIII-tubulin and γ-tubulin in diffuse-type astrocytic gliomas (grades II-IV) (n = 17) and the human glioblastoma cell line T98G. By immunohistochemistry and immunofluorescence… CONTINUE READING

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