Class III β-Tubulin Overexpression Is a Marker of Poor Clinical Outcome in Advanced Ovarian Cancer Patients

@inproceedings{Ferrandina2006ClassI,
  title={Class III β-Tubulin Overexpression Is a Marker of Poor Clinical Outcome in Advanced Ovarian Cancer Patients},
  author={Gabriella Ferrandina and Gian F Zannoni and Enrica Martinelli and Amelia Paglia and Valerio Gallotta and Simona Mozzetti and Giovanni Scambia and Cristiano Ferlini},
  year={2006}
}
Purpose: Overexpression of β III tubulin has been involved in paclitaxel resistance in several experimental models. We investigated the role of β III tubulin as predictor of clinical outcome in ovarian cancer patients given platinum/paclitaxel treatment. We also investigated whether β III tubulin expression could be modified after the selective pressure represented by chemotherapy in vivo . Experimental Design: The study was designed to include a series of consecutive ovarian cancer patients… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 28 CITATIONS