Class II MHC–independent suppressive adhesion of dendritic cells by regulatory T cells in vivo

Abstract

Regulatory T (T reg) cells are essential for peripheral homeostasis and known to target and suppress dendritic cells (DCs). One important mechanism is through prolonged interaction between antigen-specific T reg cells and DCs that down-regulates the co-stimulatory capacity of DCs. However, the dynamics and TCR specificities of such T reg cell-DC interaction… (More)
DOI: 10.1084/jem.20160629

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