Class II 3-hydroxy-3-methylglutaryl coenzyme A reductases.

  title={Class II 3-hydroxy-3-methylglutaryl coenzyme A reductases.},
  author={Matija Hedl and Lydia Tabernero and Cynthia V Stauffacher and Victor W. Rodwell},
  journal={Journal of bacteriology},
  volume={186 7},
The biosynthesis of isopentenyl diphosphate (isopentenyl pyrophosphate), the precursor of isoprenoids in all forms of life, occurs by two distinct metabolic pathways, the mevalonate pathway (Fig. 1) and the glyceraldehyde 3-phosphate/pyruvate pathway, often termed the nonmevalonate pathway (17). Whereas many gram-negative bacteria employ the nonmevalonate… CONTINUE READING