Class A scavenger receptors mediate cell adhesion via activation of G(i/o) and formation of focal adhesion complexes.

Abstract

Class A macrophage scavenger receptors (SR-A) are multifunctional receptors with roles in modified lipoprotein uptake, innate immunity, and macrophage adhesion. Our previous studies conducted in mouse peritoneal macrophages demonstrated that pertussis toxin (PTX) mediated inhibition of G(i/o) attenuated SR-A-dependent uptake of modified lipoprotein. The… (More)

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@article{Post2002ClassAS, title={Class A scavenger receptors mediate cell adhesion via activation of G(i/o) and formation of focal adhesion complexes.}, author={Steven R Post and Cecelia Gass and Stuart Alan Rice and Dejan Nikolic and Heather Louise Crump and Ginell R. Post}, journal={Journal of lipid research}, year={2002}, volume={43 11}, pages={1829-36} }