Clarithromycin suppresses invasiveness of human lung adenocarcinoma cells.

Abstract

BACKGROUND It has been speculated that clarithromycin (CAM), a 14-membered ring macrolide, possesses antitumor effects besides antimicrobial and anti-inflammatory effects. METHOD We evaluated the effects of CAM on the growth and invasiveness of A549 lung adenocarcinoma cells. RESULTS Although CAM did not affect the growth of A549 cells, the Matrigel… (More)

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