Clara cell secretory protein gene expression in bronchiolar epithelium.

@article{Hackett1992ClaraCS,
  title={Clara cell secretory protein gene expression in bronchiolar epithelium.},
  author={Brian P. Hackett and Nobuyoshi Shimizu and Jonathan D. Gitlin},
  journal={The American journal of physiology},
  year={1992},
  volume={262 4 Pt 1},
  pages={L399-404}
}
To determine the mechanisms of Clara cell secretory protein (CCSP) gene expression, a cDNA clone was isolated and used in RNA blot analysis. A single 600 bp CCSP specific transcript was detected in the developing rat lung on fetal day 18. This transcript increased in abundance during late fetal life such that adult levels were attained within 2 wk postpartum. CCSP gene expression was tissue specific, being confined to lung and trachea at all developmental stages. The abundance of CCSP mRNA in… CONTINUE READING