Clara cell protein-positive epithelial cells are reduced in small airways of asthmatics.

@article{Shijubo1999ClaraCP,
  title={Clara cell protein-positive epithelial cells are reduced in small airways of asthmatics.},
  author={Noriharu Shijubo and Yoshihisa Itoh and Tamami Yamaguchi and A. Imada and Masao Hirasawa and T Yamada and Taro Kawai and Shosaku Abe},
  journal={American journal of respiratory and critical care medicine},
  year={1999},
  volume={160 3},
  pages={930-3}
}
Clara cell 10 kilodalton protein (CC10), the predominant product from nonciliated cells in the epithelial lining of bronchioles (Clara cells), has been shown to have immunomodulatory and anti-inflammatory activity, and may play roles in controlling inflammation in the airway. This study was designed to examine immunohistochemical expression of CC10 in epithelial cells in small airways (perimeter < 6 mm) of asthmatic and control nonsmokers who underwent lung resection because of peripheral lung… CONTINUE READING