Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells

@inproceedings{Kim2012CitrusAF,
  title={Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells},
  author={Gon Sup Kim and Hyoung Joon Park and Jong-Hwa Woo and Mi-Kyeong Kim and Phil Ok Koh and Wongi Min and Yeoung-Gyu Ko and Chung-Hei Kim and Chung-Kil Won and Jae-Hyeon Cho},
  booktitle={BMC complementary and alternative medicine},
  year={2012}
}
BACKGROUND Obesity is a health hazard that is associated with a number of diseases and metabolic abnormalities, such as type-2 diabetes, hypertension, dyslipidemia, and coronary heart disease. In the current study, we investigated the effects of Citrus aurantium flavonoids (CAF) on the inhibition of adipogenesis and adipocyte differentiation in 3T3-L1 cells. METHODS During adipocyte differentiation, 3T3-L1 cells were treated with 0, 10, and 50 μg/ml CAF, and then the mRNA and protein… CONTINUE READING