Citrullinated peptides in the diagnosis of rheumatoid arthritis.

  title={Citrullinated peptides in the diagnosis of rheumatoid arthritis.},
  author={Mar{\'i}a Jos{\'e} G{\'o}mara and Isabel Haro},
  journal={Current topics in medicinal chemistry},
  volume={13 6},
Antibodies directed against citrullinated proteins and peptides (ACPAs) are the most specific serological markers available for diagnosing rheumatoid arthritis (RA). ACPAs may be detected several years before symptoms of RA appear, and their presence at disease onset is a good predictor of the development of erosive joint lesions. RA patients can be… CONTINUE READING