Citrullinated collagens in the pathogenesis of rheumatoid arthritis.

Abstract

Citrulline formation through the deimination of arginine residues has recently been identified as an enzymatic post-translational modification of proteins that could be related to breaking the tolerance to self-antigens in the development of rheumatoid arthritis. Autoantibodies recognizing citrullinated peptides are highly specific indicators of early… (More)
DOI: 10.1586/1744666X.3.2.187

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@article{Risteli2007CitrullinatedCI, title={Citrullinated collagens in the pathogenesis of rheumatoid arthritis.}, author={Juha P Risteli and Marja-Kaisa Koivula and Leila Risteli}, journal={Expert review of clinical immunology}, year={2007}, volume={3 2}, pages={187-94} }