Citrobacter rodentium espB is necessary for signal transduction and for infection of laboratory mice.

@article{Newman1999CitrobacterRE,
  title={Citrobacter rodentium espB is necessary for signal transduction and for infection of laboratory mice.},
  author={Joseph V. Newman and Brian A. Zabel and Samradhni S Jha and David B. Schauer},
  journal={Infection and immunity},
  year={1999},
  volume={67 11},
  pages={6019-25}
}
Citrobacter rodentium is the causative agent of transmissible murine colonic hyperplasia and contains a locus of enterocyte effacement (LEE) similar to that found in enteropathogenic Escherichia coli (EPEC). EPEC espB is necessary for intimate attachment and signal transduction between EPEC and cultured cell monolayers. Mice challenged with wild-type C. rodentium develop a mucosal immunoglobulin A response to EspB. In this study, C. rodentium espB has been cloned and its nucleotide sequence has… CONTINUE READING
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