Citalopram inhibits platelet function independently of SERT-mediated 5-HT transport

Abstract

Citalopram prevents serotonin (5-HT) uptake into platelets by blocking the serotonin reuptake transporter (SERT). Although some clinical data suggest that selective serotonin reuptake inhibitors (SSRIs) may affect haemostasis and thrombosis, these poorly-characterised effects are not well understood mechanistically and useful in vitro data is limited. We… (More)
DOI: 10.1038/s41598-018-21348-3

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