Citalopram for post-stroke pathological crying

@article{Andersen1993CitalopramFP,
  title={Citalopram for post-stroke pathological crying},
  author={Grethe Andersen and Karsten Vestergaard and Jens {\O}stergaard Riis},
  journal={The Lancet},
  year={1993},
  volume={342},
  pages={837-839}
}

Paroxetine versus citalopram treatment of pathological crying after brain injury.

TLDR
Rap onset (within 1-3 days) and highly significant (p < 0.001) improvements of emotionalism were observed after both paroxetine and citalopram, and there were no efficacy differences, despite the longer symptom duration in the cITALopram group.

Post‐stroke pathological crying: frequency and correlation to depression

TLDR
Post‐stroke pathological crying was common and persistent in 11% of patients at 1 year and correlated strongly to mood score and post‐stroke depression, and the indication for treatment of pathological crying is further strengthened.

Lamotrigine treatment for post-stroke pathological laughing and crying.

TLDR
A 60-year-old woman developed PLC after an ischemic stroke and was treated with lamotrigine initially at the dose of 50mg a day, which was gradually increased to 100 mg a day over a 4-week period, showing a significant and rapid recovery in both laughing and crying components of PCL with lamOTrigine treatment.

Prediction of the response to citalopram and reboxetine in post-stroke depressed patients

TLDR
Citalopram or other SSRIs and reboxetine may be of first choice treatment in PSD because of their good efficacy and lack of severe side effects.

Mirtazapine treatment for pathological laughing and crying after stroke.

TLDR
This is one of the first reports to suggest that mirtazapine may be an alternative to SSRIs for treating poststroke PLC, and both the laughing and crying spells of a 64-year-old woman were improved within a few days of mirtzapine administration.

Treatment of Uncontrolled Crying After Stroke

TLDR
The present treatment possibilities can significantly improve quality of life for patients with post-stroke pathological crying, and there seems to be a rationale for the latter approach.

Fluoxetine Treatment in Poststroke Depression, Emotional Incontinence, and Anger Proneness: A Double-Blind, Placebo-Controlled Study

TLDR
Fluoxetine significantly improved PSEI and PSAP, whereas no definitive improvement of PSD was found and its effect on PSD is not solidly confirmed.

Pathological crying and laughing: treatment with sertraline.

Memantine may affect pseudobulbar affect in patients with Alzheimer's disease

TLDR
In a limited number of AD patients with PBA, memantine had a beneficial effect on involuntary emotional expression, but it potentiated agitation/aggression, irritability and caused a crucial drop of the platelet 5-HT concentration.

Cough Suppressant and Fluoxetine in the Treatment of Pseudobulbar Affect: A Case Report

CASE REPORT A 53-year-old lady was referred to the neuropsychiatry outpatient clinic with a 15-year history of pathological crying. This occurred on a background of relapsing remitting multiple
...

References

SHOWING 1-10 OF 13 REFERENCES

Treatment of pathologic laughing and weeping with amitriptyline.

TLDR
It is concluded that amitriptyline is effective in the treatment of this disturbance of affective expression, and that this effect is distinct from the antidepressant effect of the medication.

Emotionalism after stroke.

TLDR
Emotionalism is common after stroke and is associated with symptoms of a more general mood disturbance and is found especially in patients with left frontal and temporal lesions.

Pathologic laughing and crying treated with levodopa.

TLDR
Because part of pathologic laughing and crying seems to be caused by the decreased function of the dopaminergic neuron, levodopa or amantadine is worth trying.

The Use of Imipramine (“Tofranil”) and Other Psychotropic Drugs in Organic Emotionalism

TLDR
A “double-blind” form of therapeutic trial was engaged, comparing two dose strengths of imipramine with phenobarbitone and dummy tablets given in random sequence to each patient, confirming the favourable impression of imIPramine being confirmed and attempting to assess the effect on this symptom of two other drugs of related pharmacology.

Pathological Display of Affect in Patients with Depression and Right Frontal Brain Damage: An Alternative Mechanism

TLDR
The cases argue that two organic brain diseases—one structural and the other “physiopharmacological”—may interact to produce pathological display of affect that cannot be accounted for by traditional neurological explanations, and suggest that pathological affect is a valuable clinical indicator of an underlying major depression in some brain-injured patients.

A RATING SCALE FOR DEPRESSION

  • M. Hamilton
  • Psychology, Medicine
    Journal of neurology, neurosurgery, and psychiatry
  • 1960
TLDR
The present scale has been devised for use only on patients already diagnosed as suffering from affective disorder of depressive type, used for quantifying the results of an interview, and its value depends entirely on the skill of the interviewer in eliciting the necessary information.

An activities index for use with stroke patients.

TLDR
Factor analysis indicates three major factors (domestic chores, leisure/work, outdoor activities) are sex-linked, as predicted, and some evidence is noted of the sensitivity of the index to severity of stroke.

Emotionalism following brain damage: a complex phenomenon.

TLDR
In future research each component of emotionalism should be examined in detail using a standardized form of assessment.