Citalopram amplifies the influence of living conditions on mood in depressed patients enrolled in the STAR*D study

  title={Citalopram amplifies the influence of living conditions on mood in depressed patients enrolled in the STAR*D study},
  author={Flavia Chiarotti and Aurelia Viglione and Alessandro Giuliani and Igor Branchi},
  journal={Translational Psychiatry},
Selective serotonin reuptake inhibitors (SSRIs), the most commonly prescribed antidepressant drugs, have a variable and incomplete efficacy. In order to better understand SSRI action, we explored the hypothesis that SSRIs do not affect mood per se but amplify the influence of the living conditions on mood. To this aim, we exploited the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) data set, selected a subpopulation of 591 patients with an overlapping clinical history and… 

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