CitB mutation increases the alkaline protease productivity in Bacillus subtilis.

@article{Gao2010CitBMI,
  title={CitB mutation increases the alkaline protease productivity in Bacillus subtilis.},
  author={Weihua Gao and Sen Dai and Quanli Liu and Haijin Xu and M. Qiao},
  journal={The Journal of general and applied microbiology},
  year={2010},
  volume={56 5},
  pages={403-7}
}
Bacillus is remarkable for its extracellular enzyme production (Priest, 1977). When Bacillus cells exhaust the nutrients of the environment and enter into the stationary phase, neutral and alkaline proteases encoded by nprE and aprE respectively are produced and secreted to the outside environment (Chaloupka and Kreckova, 1966; Din et al., 1969). The mechanism of aprE expression has been extensively studied and so for four DNA-binding proteins have been proved to directly regulate its… CONTINUE READING

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