Cistromics of hormone-dependent cancer.


Alterations in transcription programs are a fundamental feature of cancer. Nuclear receptors, such as the estrogen receptor alpha (ERalpha) and androgen receptors (ARs), are central in this process as they can directly impact gene expression through interaction with the chromatin and subsequent association with coregulators and the transcriptional machinery… (More)
DOI: 10.1677/ERC-09-0038

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